| 发明名称 | Method for producing glufosinate P free acid | ||
| 摘要 | The present invention provides a method for producing crystalline glufosinate P free acid with high purity from glufosinate P hydrochloride salt. In addition, the present invention also provides a method comprises a process of: dissolving glufosinate P hydrochloride salt in a solvent which is a mixed solvent of water and an alcohol(s) selected from the group of methanol, ethanol, propyl alcohol and isopropyl alcohol, and a ratio of water to the alcohol(s) is from 1:3 to 1:100 by volume; crystallizing glufosinate P free acid after neutralizing by addition of a base. | ||
| 申请公布号 | US9255115(B2) | 申请公布日期 | 2016.02.09 |
| 申请号 | US201214348376 | 申请日期 | 2012.09.28 |
| 申请人 | MEIJI SEIKA PHARMA CO. LTD. | 发明人 | Nakanishi Nozomu;Ando Takashi;Minowa Nobuto;Mitomi Masaaki |
| 分类号 | C07F9/22;C07F9/30 | 主分类号 | C07F9/22 |
| 代理机构 | Greenblum & Bernstein, P.L.C. | 代理人 | Greenblum & Bernstein, P.L.C. |
| 主权项 | 1. A method for producing a compound expressed by the following formula (I): the method comprising: dissolving a compound expressed by the following formula (II): in a solvent which is a mixed solvent of water and methanol, and a ratio of water to methanol is from 1:3 to 1:100 by volume; neutralizing the resultant solution by adding a base; and thereafter crystallizing the compound expressed by formula (I). | ||
| 地址 | Tokyo JP | ||