Immunoreactive <i>Ehrlichia </i>p120/p140 epitopes and uses thereof

摘要

Provided herein are immunoreactive peptides which can selectively bind Ehrlichia-specific anti-p120 or anti-p140 antibodies. Methods and kits utilizing the immunoreactive peptides are also provided. The immunoreactive peptides may be utilized, e.g., for determining whether or not a subject is infected with Ehrlichia chaffeensis or Ehrlichia canis. In certain embodiments, the immunoreactive peptides may be utilized in an ELISA or lateral flow assay.

主权项

1. A method of detecting antibodies that specifically bind an Ehrlichia antigenic polypeptide in a test sample of a subject suspected of having an Ehrlichia infection, comprising detecting in said sample the presence of an antibody that immunologically reacts with a polypeptide consisting of SEQ ID NO:1 or SEQ ID NO:2.