发明名称 |
ANTI-INFLAMMATORY PROPERTIES OF A SURFACE PROTEIN OF PROPIONIBACTERIUM FREUDENREICHII |
摘要 |
<p>The present invention relates to a polypeptide comprising or consisting of the amino acid sequence SEQ id n°:1, for use in the treatment or prevention of an inflammatory disease. The invention further encompasses a nucleic acid sequence encoding a polypeptide of the invention, a vector comprising a nucleic acid of the invention and a host cell comprising a nucleic acid sequence and/or a vector of the invention, for use in the treatment or prevention of an inflammatory disease. The invention also concerns a pharmaceutical composition or a food composition comprising a polypeptide, a nucleic acid sequence, a vector or a host cell of the invention and a pharmaceutically acceptable carrier or a dairy product, for the treatment of inflammatory disease. The invention also relates a method for the screening of bacteria having immunomodulatory properties.</p> |
申请公布号 |
WO2016008571(A1) |
申请公布日期 |
2016.01.21 |
申请号 |
WO2015EP01379 |
申请日期 |
2015.07.07 |
申请人 |
INSTITUT NATIONAL DE LA RECHERCHE AGRONOMIQUE (INRA);INSTITUT PASTEUR DE LILLE (IPL) |
发明人 |
JAN, GWENAEL;FOLIGNE, BENOIT;FALENTIN, HÉLÈNE;DEUTSCH, STÉPHANIE-MARIE |
分类号 |
A61K38/16;A61P29/00 |
主分类号 |
A61K38/16 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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