Systems and methods for treatment planning based on plaque progression and regression curves

摘要

Systems and methods are disclosed for evaluating a patient with vascular disease. One method includes receiving patient-specific data regarding a geometry of the patient's vasculature; creating an anatomic model representing at least a portion of a location of disease in the patient's vasculature based on the received patient-specific data; identifying one or more changes in geometry of the anatomic model based on a modeled progression or regression of disease at the location; calculating one or more values of a blood flow characteristic within the patient's vasculature using a computational model based on the identified one or more changes in geometry of the anatomic model; and generating an electronic graphical display of a relationship between the one or more values of the calculated blood flow characteristic and the identified one or more changes in geometry of the anatomic model.

主权项

1. A computer-implemented method of evaluating a patient with vascular disease, the method comprising:
receiving patient-specific data regarding a geometry of the patient's vasculature; determining a plaque remodeling characteristic characterizing a propensity of the disease in the patient's vasculature to progress or regress; determining, using the received patient-specific data and the determined plaque remodeling characteristic, a geometric model of a progression or regression of disease at a location in the patient's vasculature; calculating a value of a blood flow characteristic within the patient's vasculature using a blood flow model determined based on the received patient-specific data and the determined plaque remodeling characteristic; and generating a treatment recommendation or risk assessment based on the value of the blood flow characteristic calculated using the blood flow model based on the received patient-specific data and the determined plaque remodeling characteristic.