AUTOANTIGENS FOR DIAGNOSIS OF CHRONIC INFLAMMATORY DISEASES

摘要

Disclosed herein are methods of diagnosing Lyme arthritis in a subject comprising determining whether the subject is immunologically reactive with one or more of annexin A2, Apolipoprotein B (ApoB), and matrix metalloproteinase 10 (MMP10), wherein immunological reactivity of the subject to one or more of annexin A2, ApoB, and MMP10, as compared to an appropriate control, indicates the subject has Lyme arthritis. Methods of treatment and kits for performing the methods are also disclosed.