MAGNETIC RESONANCE SYSTEM AND METHOD TO DETECT AND CONFIRM ANALYTES

摘要

A system and method are provided to detect target analytes based on magnetic resonance measurements. Magnetic structures produce distinct magnetic field regions having a size comparable to the analyte. When the analyte is bound in those regions, magnetic resonance signals from the sample are changed, leading to detection of the analyte.

主权项

1. A magnetic resonance system comprising:
a magnet system which generates a magnetic field in a sample area; a pulse generator configured to produce electromagnetic pulses at a selected frequency; a coil coupled to the pulse generator and configured to transmit the electromagnetic pulses generated by the pulse generator to the sample area and to receive responsive magnetic resonance signals from the sample area; a receiver coupled to the coil so as to receive the magnetic resonance signals from the coil and configured to convert the magnetic resonance signals into a digital form; and a controller in communication with the pulse generator and the receiver, and configured to control the operation of the pulse generator so as to cause the pulse generator to produce electromagnetic pulses at a selected frequency; said controller being further configured to receive the digital form of the magnetic resonance signals from the receiver caused by the electromagnetic pulses being transmitted to the sample area by the coil in the presence of the magnetic field, and to analyze the digital form of the magnetic resonance signals.