发明名称 HIGHLY GALACTOSYLATED ANTI-TNF-ALPHA ANTIBODIES AND USES THEREOF
摘要 In one aspect, the disclosure relates to highly galactosylated anti-TNF-alpha antibodies and compositions thereof. In one aspect, the disclosure relates to populations of anti-TNF-alpha antibodies with a high level of galactosylation, and compositions thereof. In one aspect, the disclosure relates to methods of production and use of highly galactosylated anti-TNF-alpha antibodies and populations of anti-TNF-alpha antibodies with a high level of galactosylation. In some embodiments, the anti-TNF-alpha antibody is adalimumab.
申请公布号 US2015368334(A1) 申请公布日期 2015.12.24
申请号 US201414767117 申请日期 2014.02.13
申请人 LABORATOIRE FRANÇAIS DU FRACTIONNEMENT ET DES BIOTECHNOLOGIES 发明人 Meade Harry M.;Chen Li-How
分类号 C07K16/24 主分类号 C07K16/24
代理机构 代理人
主权项 1. An anti-TNF-alpha antibody, wherein the antibody is highly galactosylated.
地址 Les Ulis FR