发明名称 Bicyclic sulfonamide compounds as sodium channel inhibitors
摘要 The present invention provides compounds of Formula I, and pharmaceutically acceptable salts thereof, that are inhibitors of voltage-gated sodium channels, in particular Nav1.7. The compounds are useful for the treatment of diseases associated with the activity of sodium channels such as pain disorders and itch. Also provided are pharmaceutical compositions containing compounds of the present invention.
申请公布号 AU2014278126(A1) 申请公布日期 2015.12.24
申请号 AU20140278126 申请日期 2014.06.12
申请人 AMGEN INC. 发明人 WEISS, MATTHEW;BOEZIO, ALESSANDRO;BOEZIO, CHRISTIANE;BUTLER, JOHN R.;CHU-MOYER, MARGARET YUHUA;DIMAURO, ERIN F.;DINEEN, THOMAS;GRACEFFA, RUSSELL;GUZMAN-PEREZ, ANGEL;HUANG, HONGBIN;KREIMAN, CHARLES;LA, DANIEL;MARX, ISAAC E.;MILGRIM, BENJAMIN CHARLES;NGUYEN, HANH NHO;PETERSON, EMILY;ROMERO, KARINA;SPARLING, BRIAN
分类号 C07D403/12;A61K31/4704;A61P29/00;C07D215/36;C07D241/44;C07D413/12;C07D413/14;C07D417/12 主分类号 C07D403/12
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