PLACENTA GROWTH FACTOR IN TREATING DUCHENNE MUSCULAR DYSTROPHY

摘要

The present invention provides, among other things, methods and compositions for treating muscular dystrophy, in particular, Duchenne muscular dystrophy (DMD). In some embodiments, a method according to the present invention includes administering to an individual who is suffering from or susceptible to DMD an effective amount of a recombinant PLGF protein such that at least one symptom or feature of DMD is reduced in intensity, severity, or frequency, or has delayed onset. The present invention also provides exemplary recombinant PLGF proteins including monomeric, dimeric and single-chain PLGF proteins.

主权项

1. A method of treating Duchenne Muscular Dystrophy (DMD) comprising administering to an individual who is suffering from or susceptible to DMD an effective amount of a recombinant placenta growth factor (PLGF) protein such that at least one symptom or feature of DMD is reduced in intensity, severity, or frequency, or has delayed onset.