发明名称 Notch pathway signaling inhibitor compound
摘要 <p>Provided is the compound 4,4,4-trifluoro-N-[(1S)-2-[[(7S)-5-(2-hydroxyethyl)-6-oxo-7H-pyrido[2,3-d][3] benzazepin-7-yl]amino]-1-methyl-2-oxo-ethyl]butanamide. The compound is a Notch pathway signalling inhibitor. The compound may be useful for the treatment of cancer. Further disclosed is a crystalline hydrate of 4,4,4-trifluoro-N-[(1S)-2-[[(7S)-5-(2-hydroxyethyl)-6-oxo-7H-pyrido[2,3-d][3] benzazepin-7-yl]amino]-1-methyl-2-oxo-ethyl]butanamide.</p>
申请公布号 NZ618891(A) 申请公布日期 2015.12.24
申请号 NZ20120618891 申请日期 2012.07.18
申请人 ELI LILLY AND COMPANY 发明人 HIPSKIND PHILIP ARTHUR;STEPHENSON GREGORY ALAN
分类号 C07K5/06;A61K38/05;A61P35/00;A61P35/02;C07D471/04 主分类号 C07K5/06
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