摘要 |
<p>Provided is the compound 4,4,4-trifluoro-N-[(1S)-2-[[(7S)-5-(2-hydroxyethyl)-6-oxo-7H-pyrido[2,3-d][3] benzazepin-7-yl]amino]-1-methyl-2-oxo-ethyl]butanamide. The compound is a Notch pathway signalling inhibitor. The compound may be useful for the treatment of cancer. Further disclosed is a crystalline hydrate of 4,4,4-trifluoro-N-[(1S)-2-[[(7S)-5-(2-hydroxyethyl)-6-oxo-7H-pyrido[2,3-d][3] benzazepin-7-yl]amino]-1-methyl-2-oxo-ethyl]butanamide.</p> |