发明名称 SOLID COMPOSITIONS COMPRISING HCV INHIBITOR
摘要 PROBLEM TO BE SOLVED: To provide a novel drug composition for treating HCV infection.SOLUTION: The invention relates to a formulation which is a noncrystalline solid dispersion, and which contains a hydrophilic polymer accepted as a medicine and preferably a surfactant accepted as a medicine in an HCV inhibitor selected from telaprevir, BI-201335, TMC-435, vaniprevir, MK-5172, asunaprevir, daclatasvir, danoprevir, setrobuvir, tegobuvir, GS-9451, mericitabine, IDX-184, filibuvir, PSI-7977, PSI-352938, BIT-225, boceprevir, GS-5885 or GS-9256. For example, the hydrophilic polymer is a homopolymer or copolymer of N-vinylpyrrolidone, and the surfactant is D-alpha-tocopheryl polyethylene glycol 1000 succinate.
申请公布号 JP2015227352(A) 申请公布日期 2015.12.17
申请号 JP20150140513 申请日期 2015.07.14
申请人 ABBVIE IRELAND UNLIMITED CO 发明人 GAO YI;ZHANG GEOFF G Z
分类号 A61K45/00;A61K9/14;A61K47/32;A61K47/34;A61P31/14 主分类号 A61K45/00
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