发明名称 |
ISOFLAVONE DERIVATIVES AND USES THEREOF |
摘要 |
<p>Isoflavone derivatives are provided comprising a carboxyalkylene moiety linked via its alkylene chain to the aromatic ring and via its carboxy group to an aminoalkyleneamino residue, which, in turn, is covalently linked to a functional group B. The isoflavone derivatives are preferably derived from biochanin A, genistein, and daidzein, and the functional group B is preferably an amino protecting group. These isoflavone derivatives are useful for treating or preventing diseases or disorders associated with estrogen receptor functioning.</p> |
申请公布号 |
EP2121650(A1) |
申请公布日期 |
2009.11.25 |
申请号 |
EP20080710219 |
申请日期 |
2008.02.20 |
申请人 |
YEDA RESEARCH AND DEVELOPMENT CO. LTD.;MEDICAL RESEARCH AND INFRASTRUCTURE FUND OF TEL-AVIV SOURASKY MEDICAL CENTER |
发明人 |
KOHEN, FORTUNE;SOMJEN, DALIA;STERN, NAFTALI;FRYDMAN, VERONICA;KULIK, TIKVA;GAYER, BATYA |
分类号 |
C07D311/36;A61K31/352;A61P35/00 |
主分类号 |
C07D311/36 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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