Xanthine derivatives as A2B adenosine receptor antagonists suitable for treating conditions such as asthma and diarrhoea

摘要

Disclosed are compounds of formulae I and II, wherein X is optionally substituted arylene and the other substituents are as defined in the specification. The compounds are A2B adenosine receptor antagonists suitable for treating conditions such as atherosclerosis, angiogenesis, type II diabetes, diabetic retinopathy, cancer, asthma, inflammatory gastrointestinal tract disorders including diarrhea, and neurological disorders including senile dementia, Alzheimer's disease and Parkinson's disease. (62) Divided Out of 543416