发明名称 |
ANTIKÖRPER GEGEN HUMANES CD22 UND DEREN THERAPEUTISCHE UND DIAGNOSTISCHE VERWENDUNGEN |
摘要 |
There is disclosed antibody molecules containing at least one CDR derived from a mouse monoclonal antibody having specificity for human CD22. There is also disclosed a CDR grafted antibody wherein at least one of the CDRs is a modified CDR. Further disclosed are DNA sequences encoding the chains of the antibody molecules, vectors, transformed host cells and uses of the antibody molecules in the treatment of diseases mediated by cells expressing CD22. |
申请公布号 |
DE60331910(D1) |
申请公布日期 |
2010.05.12 |
申请号 |
DE2003631910 |
申请日期 |
2003.05.02 |
申请人 |
UCB PHARMA, S.A. |
发明人 |
POPPLEWELL, ANDREW GEORGE;TICKLE, SIMON PETER;LADYMAN, HEATHER MARGARET |
分类号 |
C07K16/18;C07K16/28;A61K31/7088;A61K38/16;A61K39/395;A61P35/00;C12N5/10;C12N15/13;C12N15/63;C12N15/85;C12P21/00 |
主分类号 |
C07K16/18 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|