摘要 |
FIELD: medicine. ^ SUBSTANCE: invention relates to field of medicine and deals with immunogenic composition. Essence of invention consists in development of immunogenic composition, obtained by culturing transformant of avirulent dividing yeasts-hosts Schizosaccharomyces pombe, in which transformant carries gen, which codes introduced into it antigen protein, representing capsid protein of L1 virus of human papilloma of 16 (HPV-16) type and accumulates in itself expressed antigen protein, for oral application. ^ EFFECT: development of immunogenic composition for oral application. ^ 3 cl, 5 ex, 2 tbl, 5 dwg |