Method For Producing T Cell Receptor-Like Monoclonal Antibodies And Uses Thereof

摘要

METHOD FOR PRODUCING T CELL RECEPTOR-LIKE MONOCLONAL Methods axe provided for producing cell receptor (TCR) T like antibodies that recognize peptides displayed in the context of HLA molecules. Antibodies produced by methods provided herein have the specificity of a TCR and can be used as therapeutic, diagnostic and research reagents. Also provided are TCR-like antibodies which recognize Epstein-Barr virus (EBV) peptides displayed in the context of HLA molecules and are useful for the detection and treatment of EBV and EBV-linked diseases. (Figure 1) -60-