发明名称 |
COMPOSITIONS, METHODS AND KITS FOR DIAGNOSING AND TREATING CD206 EXPRESSING CELL-RELATED DISORDERS |
摘要 |
<p>A method of diagnosing a CD206 expressing cell-related disorder by administering a pharmaceutical composition to a subject, the composition including a carrier molecule having a detectable moiety attached thereto. The carrier molecule has a dextran backbone, and at least one receptor substrate conjugated, directly or indirectly, to the dextran backbone, wherein the receptor substrate is chosen so as to specifically bind to CD206. A method of treating a CD206 expressing cell-related disorder is also provided, as well as an ex vivo method and kit for quantitating the number of cells expressing CD206 in a bodily fluid.</p> |
申请公布号 |
WO2015013341(A1) |
申请公布日期 |
2015.01.29 |
申请号 |
WO2014US47708 |
申请日期 |
2014.07.22 |
申请人 |
NAVIDEA BIOPHARMACEUTICALS, INC.;OHIO STATE INNOVATION FOUNDATION |
发明人 |
COPE, FREDERICK;BLUE, MICHAEL;METZ, WENDY;SCHLESINGER, LARRY |
分类号 |
A61K47/48;A61K49/00;A61K51/04;A61K51/06;A61K103/00;A61K103/10;A61P19/02;A61P31/06;A61P35/00 |
主分类号 |
A61K47/48 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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