| 发明名称 |
7-[3,5-DIHYDROXY-2-(3-HYDROXY-5-PHENYL-PENT-1-ENYL)-CYCLOPENTYL]-N- ETHYL-HEPT-5-ENAMIDE (BIMATOPROST) IN CRYSTALLINE FORM II, METHODS FOR PREPRATION, AND METHODS FOR USE THEREOF |
| 摘要 |
<p>The present invention provides a new crystalline form of bimatoprost, designated as crystalline form 11. This new crystalline form is the most stable form known to date of bimatoprost. Moreover, it has been found that bimatoprost crystalline form I1 is readily prepared from crystalline form I.</p> |
| 申请公布号 |
IN5209DEN2012(A) |
申请公布日期 |
2015.10.23 |
| 申请号 |
IN2012DE05209 |
申请日期 |
2012.06.13 |
| 申请人 |
ALLERGAN, INC. |
发明人 |
GYORGY F. AMBRUS;KIOMARS KARAMI;KE WU |
| 分类号 |
C07C405/00 |
主分类号 |
C07C405/00 |
| 代理机构 |
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