Pharmaceutical compositions with glycosaminoglycans and use thereof in the treatment of chronic ulcers

摘要

The invention relates to a composition of glycosaminoglycans for the treatment of diabetic foot ulcer, it specifically relates to low molecular weight heparins (LMWHs) and very low molecular weight heparins (VLMWHs) in the treatment of chronic ulcers, particularly of diabetic foot ulcers, and more specifically in the manufacture of a medicinal product for the treatment of chronic ulcers, and particularly diabetic foot ulcers and pressure ulcers.

主权项

1. A method of treating chronic foot ulcer in a diabetic subject having peripheral arterial occlusive disease comprising administering to the subject a daily dose of low molecular weight or very low molecular weight heparin having a plasma half-life ranging from 3 to 6.9 hours, wherein the average daily dose ranges from 5,000-10,000 IU.