| 发明名称 |
PREPARATION OF 7-DEHYDROCHOLESTEROL AND/OR THE BIOSYNTHETIC INTERMEDIATES AND/OR SECONDARY PRODUCTS THEREOF IN TRANSGENIC ORGANISMS |
| 摘要 |
The present invention relates to a method for preparing 7-dehydrocholesterol and/or the biosynthetic intermediates and/or secondary products thereof by culturing organisms, in particular yeasts. Furthermore, the invention relates to the preparation of the nucleic acid constructs required for preparing the genetically modified organisms and to said genetically modified organisms, in particular yeasts, themselves. |
| 申请公布号 |
US2015353980(A1) |
申请公布日期 |
2015.12.10 |
| 申请号 |
US201414583418 |
申请日期 |
2014.12.26 |
| 申请人 |
Lang Christine;Veen Markus |
发明人 |
Lang Christine;Veen Markus |
| 分类号 |
C12P33/00;C12N15/81;C12N9/02;C12N15/52;C12N9/90 |
主分类号 |
C12P33/00 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A method for preparing 7-dehydrocholesterol and/or the biosynthetic intermediates and/or secondary products thereof by culturing organisms which, compared to the wild type, have an increased activity of at least one of the activities selected from the group consisting of Δ8-Δ7-isomerase activity, Δ5-desaturase activity and Δ24-reductase activity. |
| 地址 |
Berlin DE |
