ORALLY DISINTEGRATING TABLET CONTAINING ASENAPINE

摘要

The present invention relates to an orally disintegrating tablet (ODT) containing asenapine maleate and to a process for preparing the ODT. In a first aspect, the present invention relates to an ODT containing asenapine maleate and low substituted hydroxypropylcellulose. In a second aspect, the present invention relates to an ODT containing crystalline asenapine maleate and the ODT is prepared using conventional tabletting techniques as direct compression and granulation. In a third aspect, the present invention relates to an ODT containing asenapine maleate and a carboxylic acid, and to the use of a carboxylic acid for enhancing storage stability of an asenapine maleate containing ODT.

主权项

1. Orally disintegrating tablet containing asenapine maleate, low substituted hydroxypropylcellulose (L-HPC) and/or a carboxylic acid, and a pharmaceutical excipient.