SYSTEMS AND METHODS FOR REAL-TIME TUMOR TRACKING

摘要

Various embodiments disclose systems and methods for tracking regions (e.g., tumor locations) within living organisms. Some embodiments provide real-time, highly accurate, low latency measurements of tumor location even as the tumor moves with internal body motions. Such measurements may be suitable for closed-loop radiation delivery applications where radiation therapy may be continuously guided to the tumor site even as the tumor moves. Tumor motion may be associated with periodic motion (e.g., respiratory, cardiac) or aperiodic motion (e.g., gross patient motion, internal bowel motion). Various embodiments facilitate accurate radiation delivery to tumor sites exhibiting significant motion, e.g., lung, breast, and liver tumors.

主权项

1. A computer-implemented method, comprising:
determining a first position of a first fiducial of a plurality of fiducials, the plurality of fiducials located in or on a portion of a human body, the plurality of fiducials each associated with a plurality of preliminary positions; predicting a first plurality of positions associated with the plurality of fiducials based upon the determined position of the first fiducial and the plurality of preliminary positions; determining a first target position based upon the first plurality of positions; determining a second position of a second fiducial of the plurality of fiducials; predicting a second plurality of positions associated with the plurality of fiducials based upon the determined second position of the second fiducial; and determining a second target position based upon the second plurality of positions.