| 主权项 |
1. A device for detecting fatty acid binding protein (FABP) in a blood sample from a patient, the device comprising the following elements:
a) separator for separating blood into blood plasma and red blood cells, wherein said separator comprises:
a chamber for receiving a blood sample and comprising a diluent for said blood sample;a filter through which blood plasma from a diluted blood sample and said FABP, optionally complexed to an antibody, can pass but at least red blood cells cannot, anda pressurizor that presses through said filter at least part of the blood sample to provide separated blood plasma, and b) a collector for the separated blood plasma, wherein said separator and/or said collector and/or said diluent is provided with a detection-antibody against a first epitope of FABP, said detection-antibody being conjugated with a detectable label and contacts blood plasma, and said collector is provided with a capture-antibody against a second epitope of FABP which is different from said first epitope, wherein said capture-antibody is provided in said collector in immobilized form and contacts said separated blood plasma, and wherein said filter is provided at or near the end of a tubular element which can be inserted in said chamber, and wherein said collector is formed by the interior part of said tubular element. |
