Magnetic Retention of Regenerative Cells for Wound Repair

摘要

Methods are disclosed for promoting wound repair, by magnetically retaining or confining stem cells, or other cells capable of generating the desired tissue, in a target region (e.g., a wound) where tissue regrowth is needed. Also disclosed are magnetic particles and magnetically inducible particles for these methods, as well as sheets comprising magnetic materials.

主权项

1. A method for promoting wound repair in a patient, the method comprising:
(a) implanting a plurality of magnetic particles or magnetically inducible particles in the patient, proximate a target region; and (b) delivering, to the target region, regenerative cells complexed with a magnetizable substrate,wherein, following steps (a) and (b), the regenerative cells complexed with the magnetizable substrate are within a magnetic field of the magnetic particles, or of the magnetically inducible particles when the magnetic field is induced.