发明名称 |
Polymer membranes for continuous analyte sensors |
摘要 |
Devices and methods are described for providing continuous measurement of an analyte concentration. In some embodiments, the device has a sensing mechanism and a sensing membrane that includes at least one surface-active group-containing polymer and that is located over the sensing mechanism. The sensing membrane may have a bioprotective layer configured to substantially block the effect and/or influence of non-constant noise-causing species. |
申请公布号 |
US9173606(B2) |
申请公布日期 |
2015.11.03 |
申请号 |
US201414169018 |
申请日期 |
2014.01.30 |
申请人 |
DexCom, Inc. |
发明人 |
Boock Robert;Swinney Monica Rixman;Zhang Huashi;Estes Michael J.;Lawrence Kristina |
分类号 |
A61B5/145;G01N27/40;A61B5/1468;A61B5/1473;A61B5/1486;C12Q1/00 |
主分类号 |
A61B5/145 |
代理机构 |
Knobbe Martens Olson & Bear, LLP |
代理人 |
Knobbe Martens Olson & Bear, LLP |
主权项 |
1. A system for measurement of an analyte concentration, the system comprising:
an implantable sensor comprising a sensing region configured to continuously produce in vivo sensor data indicative of an analyte concentration in a host, wherein the sensor further comprises a membrane located over the sensing region, wherein the membrane comprises a layer configured to reduce a flux of the analyte therethrough, wherein the layer comprises a material that is a polymer produced by a reaction of an isocyanate; a processor configured to process sensor data; and a user interface configured to display information corresponding to continuous sensor data; wherein the sensor is configured to provide, at analyte concentrations of from 40 mg/dL to 400 mg/dL, a level of accuracy corresponding to a mean absolute relative difference of less than 10% over a sensor session length of from 3 to 7 days, wherein one or more reference measurements used to calculate the mean absolute relative difference are determined by analysis of blood. |
地址 |
San Diego CA US |