发明名称 Adamantyl derivatives as therapeutic agents
摘要 The present invention relates to adamantyl derivatives and their anti-cancer activity. Compounds of formulae I and II are provided as well as related methods of treatment and methods of synthesis.
申请公布号 US9168237(B2) 申请公布日期 2015.10.27
申请号 US201414254397 申请日期 2014.04.16
申请人 Women & Infants' Hospital of Rhode Island 发明人 Moore Richard G.;Singh Rakesh K.
分类号 A01N37/00;A61K31/21;A61K31/198;C07C333/20;C07C331/20;A61K31/26;A61K31/27;A61K45/06 主分类号 A01N37/00
代理机构 Mintz Levin Cohn Ferris Glovsky and Popeo PC 代理人 Mintz Levin Cohn Ferris Glovsky and Popeo PC
主权项 1. A method for treating cancer in a subject in need of such treatment, the method comprising administering to said subject a therapeutically effective compound, wherein the compound comprises: or a pharmaceutically acceptable salt, prodrug, tautomer, regioisomer, stereoisomer, diastereomer, enantiomer or racemate thereof, wherein the cancer is selected from the group consisting of neuroblastoma, breast cancer, cervical cancer, prostate cancer, colon cancer, lung cancer, central nervous system cancer, renal cancer, melanoma, lymphoma, and leukemia.
地址 Providence RI US