发明名称 INHIBITORS OF SYK AND JAK PROTEIN KINASES
摘要 The present invention is directed to compounds of formula I-V and tautomers thereof or pharmaceutically acceptable salts, esters, and prodrugs thereof which are inhibitors of syk kinase. The present invention is also directed to intermediates used in making such compounds, the preparation of such a compound, pharmaceutical compositions containing such a compound, methods of inhibition syk kinase activity, methods of inhibition the platelet aggregation, and methods to prevent or treat a number of conditions mediated at least in part by syk kinase activity, such as undesired thrombosis and Non Hodgkin's Lymphoma.
申请公布号 US2015297595(A1) 申请公布日期 2015.10.22
申请号 US201414576707 申请日期 2014.12.19
申请人 Portola Pharmaceuticals, Inc. 发明人 Jia Zhaozhong J.;Venkataramani Chandrasekar;Huang Wolin;Mehrotra Mukund;Song Yonghong;Xu Qing;Bauer Shawn M.;Rose Jack W.;Kane Brian;Pandey Anjali
分类号 A61K31/506 主分类号 A61K31/506
代理机构 代理人
主权项
地址 South San Francisco CA US