| 发明名称 |
Methods of treating diseases with proanthocyanidin oligomers such as crofelemer |
| 摘要 |
<p>Disclosed herein are methods of treating diseases including gastrointestinal disorders, such as secretory diarrheas, with the proanthocyanidin oligomer, crofelemer. Also disclosed is the anti-secretory effect of crofelemer on Calcium-activated chloride channels (CaCC) and Cystic fibrosis transmembrane conductance regulator (CFTR).</p> |
| 申请公布号 |
AU2010303577(B2) |
申请公布日期 |
2015.10.22 |
| 申请号 |
AU20100303577 |
申请日期 |
2010.10.05 |
| 申请人 |
THE REGENTS OF THE UNIVERSITY OF CALIFORNIA;NAPO PHARMACEUTICALS, INC. |
发明人 |
VERKMAN, ALAN S.;CHATURVEDI, PRAVIN;TRADTRANTIP, LUKMANEE;NAMKUNG, WAN |
| 分类号 |
A61K31/74;A01N65/00 |
主分类号 |
A61K31/74 |
| 代理机构 |
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