发明名称 |
WHOLE GENOME AMPLIFICATION METHOD AND APPLICATION THEREOF |
摘要 |
Provided are a whole genome sample amplification method, a whole genome sequencing method, and a method for determining whether an abnormal state occurs in a whole genome, a whole genome sample amplification apparatus, a whole genome sequencing device, and a system for determining whether an abnormal state occurs in a whole genome. The whole genome sample amplification method comprises: subjecting a whole genome sample to a first amplification reaction, so as to obtain a first amplification product; and subjecting the first amplification product to a second amplification reaction, so as to obtain a second amplification product. The first amplification reaction is one of the PCR-based amplification reaction and the isothermal amplification reaction, and the second amplification reaction is the other of the PCR-based amplification reaction and the isothermal amplification reaction. |
申请公布号 |
US2015299753(A1) |
申请公布日期 |
2015.10.22 |
申请号 |
US201214378935 |
申请日期 |
2012.03.30 |
申请人 |
WU Kui;WU Hanjie;HOU Yong;XU Xun;WANG Jun |
发明人 |
WU Kui;WU Hanjie;HOU Yong;XU Xun;WANG Jun |
分类号 |
C12P19/34;C12Q1/68 |
主分类号 |
C12P19/34 |
代理机构 |
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代理人 |
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主权项 |
1. A method of amplifying a whole genome sample, comprising:
subjecting the whole genome sample to a first amplification reaction, to obtain a first amplification product; subjecting the first amplification product to a second amplification reaction, to obtain a second amplification product, wherein the first amplification reaction is one of a polymerase chain reaction PCR-based amplification reaction and an isothermal amplification reaction, the second amplification reaction is the other of the PCR-based amplification reaction and the isothermal amplification reaction. |
地址 |
Shenzhen CN |