发明名称 |
Method and apparatus for in vivo surveillance of circulating biological components |
摘要 |
The invention relates generally to in vivo collection of circulating molecules, tumor cells and other biological markers using a collecting probe. The probe is configured for placement within a living organism for an extended period of time to provide sufficient yield of biological marker for analysis. |
申请公布号 |
US9162884(B2) |
申请公布日期 |
2015.10.20 |
申请号 |
US201113333876 |
申请日期 |
2011.12.21 |
申请人 |
John Wayne Cancer Institute |
发明人 |
Hoon David;Taback Bret;Shaolian Samuel |
分类号 |
C12M1/34;B82Y30/00;G01N33/543 |
主分类号 |
C12M1/34 |
代理机构 |
Knobbe, Martens, Olson & Bear LLP |
代理人 |
Knobbe, Martens, Olson & Bear LLP |
主权项 |
1. A method for collecting markers associated with circulating cells, comprising the steps of:
providing a probe comprising a metallic guidewire comprising a binding surface comprising an outer porous zone and an inner non-porous zone and an atraumatic distal tip, wherein the binding surface has affixed thereto at least one binding partner for binding a marker, and wherein the binding surface is configured to immobilize a marker to the binding surface upon binding of the marker to the binding partner; positioning at least a portion of the probe in an anatomical structure of a living organism; maintaining the probe in a generally fixed position; and removing the probe from the living organism. |
地址 |
Santa Monica CA US |