Stent suitable for deployment in a blood vessel

摘要

A stent (1) comprises a central section (2), a first intermediate section (3), a first end section (4), a second intermediate section (5), and a second end section (6). The stent (1) is movable between a collapsed delivery configuration and an expanded deployment configuration. In the delivery configuration the central section (2), the first intermediate section (3), the first end section (4), the second intermediate section (5), and the second end section (6) are all cylindrically shaped. In the deployment configuration the central section (2) is helically shaped, while the first end section (4) and the second end section (6) remain cylindrically shaped. Each intermediate section (3, 5) acts as a blended region to provide a smooth transition from the helical shape of the central section (2) to the cylindrical shape of the unstented blood vessel. The radial stiffness of the stent (1) varies gradually along part of the length of the stent (1). The radial stiffness of the end region of the stent (1) is less than the radial stiffness of a first region located further in from the end of the stent (1). The variation in radial stiffness reduces the area of blood vessel wall which has low wall shear stress, reduces the possibility of recirculation, and reduces the risk of neointimal hyperplasia.

主权项

1. A stent suitable for deployment in a blood vessel to support at least part of an internal wall of the blood vessel, the stent being movable between a delivery configuration and a deployed configuration, the stent comprising a first region and two second regions, a radial stiffness of the first region being greater than a radial stiffness of each of the second regions wherein the stent has first and second ends and wherein one of the second regions is located at the first end of the stent, and the other one of the second regions is located at the second end of the stent;
wherein the stent comprises a plurality of annular elements, including at least first and second annular elements in the first region and at least one annular element in each of the second regions, the first and second annular elements in the first region being arranged longitudinally adjacent to each other and being connected together by at least one connecting element, wherein a longitudinal dimension of each of the first and second annular elements in the first region is less than a longitudinal dimension of the at least one annular element in each of the second regions, whereby the radial stiffness in each of the second regions is less than the radial stiffness in the first region due to the greater longitudinal dimension of the at least one annular element in each of the second regions than the longitudinal dimension of each of the first and second annular elements in the first region; wherein the stent extends longitudinally and has a centreline; wherein the stent has a first end section at one longitudinal end thereof and a second end section at an opposite longitudinal end thereof, and a section located between the first and second end sections; wherein in the deployed configuration the centreline of the section of the stent located between the first and second end sections is curved in three-dimensional space; and wherein in the deployed configuration the centreline of the first end section is substantially co-linear with the centreline of the second end section.