| 发明名称 |
MAMMALIAN CALCIUM CHANNELS AND RELATED PROBES, CELL LINES AND METHODS |
| 摘要 |
Sequences and sequences for types of mammalian (human and rat sequences identified) T-type calcium channel subunits which we have labeled as the ± 1 G, ± 1H and ± 11 subunits are provided. Knowledge of the sequence of these calcium channel permits the localization and recovery of the complete sequence from human cells, and the development of cell lines which express the novel calcium channels of the invention. These cells may be used for identifying compounds capable of acting as agonists or antagonists to the calcium channels.
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| 申请公布号 |
EP1780278(A2) |
申请公布日期 |
2007.05.02 |
| 申请号 |
EP20060115615 |
申请日期 |
2000.07.04 |
| 申请人 |
NEUROMED TECHNOLOGIES, INC. |
发明人 |
SNUTCH, TERRANCE P.;BAILLIE, DAVID L. |
| 分类号 |
C12N15/12;G01N33/50;A61K31/7088;A61K38/00;A61K38/17;A61K45/00;A61K48/00;A61P9/04;A61P9/06;A61P9/12;A61P25/08;A61P25/20;A61P43/00;C07K14/47;C07K14/705;C07K16/18;C07K16/28;C12N5/10;C12N15/09;C12N15/11;C12P21/02;C12Q1/02;C12Q1/68;G01N33/15;G01N33/53;G01N33/566;G01N33/58 |
主分类号 |
C12N15/12 |
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