发明名称 NEW FLUORINE-CONTAINING 1,4-DIHYDROPYRIDINES,PROCESS FOR THEIR PREPARATION AND THEIR USE AS MEDICAMENTS
摘要 Hypotensive long-acting 1,4-dihydropyridines of the formula <IMAGE> in which R1 is phenyl or heterocyclic, R2, R3, R4 and R5 have the usual definitions in such compounds, R6 represents hydrogen or a lower alkyl radical or the trifluoromethyl group, R7 and R8 each denote a hydrogen atom or a fluorine atom, n>/=1 and m>/=0, and the sum of n and m must be a least 4, and X represents a single bond, an oxygen atom or the group -N(alkyl)-O2S-, or pharmacologically acceptable acid addition salts thereof.
申请公布号 ZA8609376(B) 申请公布日期 1987.09.30
申请号 ZA19860009376 申请日期 1986.12.12
申请人 BAYER AKTIENGESELLSCHAFT 发明人 EGBERT WEHINGER;HORST MEYER;ANDREAS KNORR;STANISLAV KAZDA
分类号 A61K31/4427;A61K31/455;A61P9/08;A61P9/12;C07D211/90;C07D401/04;C07D401/06;C07D401/12;C07D413/04 主分类号 A61K31/4427
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