发明名称 |
BIOLOGICAL PACEMAKERS INCLUDING MUTATED HYPERPOLARIZATION-ACTIVATED CYCLIC NUCLEOTIDE-GATED (HCN) CHANNELS |
摘要 |
A composition for implantation into cardiac tissue includes a biological pacemaker that, when implanted, expresses an effective amount of a mutated hyperpolarization-activated and cyclic nucleotide-gated (HCN) isoform to modify Ih when compared with wild-type HCN. Methods for implementing each of the biological pacemakers include implanting each of biological pacemakers into cardiac tissue.
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申请公布号 |
US2009099611(A1) |
申请公布日期 |
2009.04.16 |
申请号 |
US20060565433 |
申请日期 |
2006.11.30 |
申请人 |
SIGG DANIEL C;SHARMA VINOD;XIAO YONG-FU |
发明人 |
SIGG DANIEL C.;SHARMA VINOD;XIAO YONG-FU |
分类号 |
A61N1/39;A61K31/7088;A61K38/00;A61K48/00;A61M31/00;A61N1/362 |
主分类号 |
A61N1/39 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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