COMPOSITIONS AND METHODS OF MODULATING AN IMMUNE RESPONSE TO AN ANTIGEN BY ADMINISTRATION OF CYTOKINE-COATED CELLS

摘要

The invention provides for a method of vaccinating a mammal to a selected antigen, wherein the method comprises administering to a mammal a vaccine composition comprising a CD40 ligand-enhanced cell, wherein the CD40 ligand-enhanced cell comprises a selected antigen and is admixed with an engineered ligand for CD40.