发明名称 Hydrazide containing taxane conjugates
摘要 The present invention relates to compounds of formula I or salts thereof, wherein, R1 is selected from the group consisting of hydrogen and R4; R2 is selected from the group consisting of hydrogen, acetyl and R4; R3 is selected from the group consisting of alkyl, —O-alkyl, —NH-alkyl, aryl and heterocyclyl; R4 represents a moiety (A) wherein, X is selected from the group consisting of a single bond, alkylene, alkenylene, alkynylene, arylene or a heterocyclylene moiety; R5 and R6 are same or different and are independently selected from hydrogen, alkyl, aryl or heterocyclyl; or R5 and R6 may form together with the nitrogen atom to which they are attached a heterocyclyl ring system.
申请公布号 US8133888(B2) 申请公布日期 2012.03.13
申请号 US20090918985 申请日期 2009.02.12
申请人 PATEL JITEN RANCHHODBHAI;PATEL GOPALKUMAR CHIMANLAL;SHETH GAURAV SANJIVKUMAR;CHITTURI TRINADHA RAO;THENNATI RAJAMANNAR;SUN PHARMA ADVANCED RESEARCH COMPANY LTD. 发明人 PATEL JITEN RANCHHODBHAI;PATEL GOPALKUMAR CHIMANLAL;SHETH GAURAV SANJIVKUMAR;CHITTURI TRINADHA RAO;THENNATI RAJAMANNAR
分类号 A61K31/337;A61K31/4523;A61K31/5377;C07D305/14;C07D405/12;C07D413/12 主分类号 A61K31/337
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