The present invention provides NOTCH1 gene mutation as a biomarker that is predictive for the response and outcome after treatment with an anti-CD20 antibody in cancer patients.
申请公布号
WO2014068133(A8)
申请公布日期
2015.01.08
申请号
WO2013EP73015
申请日期
2013.11.05
申请人
F. HOFFMANN-LA ROCHE AG;HOFFMANN-LA ROCHE INC.;UNIVERSITAETSKLINIKUM ULM;UNIVERSITAET ZU KOELN
发明人
HALLEK, MICHAEL;STILGENBAUER, STEPHAN;DÖHNER, HARTMUT;KLEIN, CHRISTIAN;UMAÑA, PABLO