发明名称 Compositions for controlling <i>Varroa </i>mites in bees
摘要 An isolated nucleic acid agent is disclosed comprising a nucleic acid sequence which downregulates expression of a gene product of a Varroa destructor mite. Compositions comprising same and uses thereof are also disclosed.
申请公布号 US8962584(B2) 申请公布日期 2015.02.24
申请号 US201213446557 申请日期 2012.04.13
申请人 Yissum Research Development Company of the Hebrew University of Jerusalem, Ltd.;Beeologics Inc. 发明人 Sela Ilan;Shafir Sharoni;Maori Eyal;Garbian Yael;Ben-Chanoch Eyal;Yarden Gal;Kalev Haim
分类号 C12N15/11;C12Q1/68;C12N15/113;A61K31/713 主分类号 C12N15/11
代理机构 Thompson Coburn LLP 代理人 Thompson Coburn LLP ;Romano Charles P.
主权项 1. A method of preventing or treating a Varroa destructor mite infestation of a bee hive, the method comprising administering to a bee of said hive an effective amount of at least one nucleic acid agent which comprises at least one ribonucleic acid sequence of a Varroa destructor mite, thereby preventing or treating a Varroa destructor mite infestation of said bee hive, wherein said gene product is selected from the group consisting of ATPase subunit A, RNA polymerase I, RNA polymerase III, Inhibitor of Apoptosis (TAP), FAS apoptotic inhibitor and alpha-Tubulin.
地址 Jerusalem IL