| 摘要 |
<p>A conventional layered tablet comprises a layer including propionic acid-based NSAIDs; and a layer including an acid scavenger. The layer including an acid scavenger may cause collapse delay after preservation. In addition, when tableting a conventional layered tablet, binding of the layer including an acid scavenger and capping of the layer including propionic acid-based NSAIDs can easily occur. Therefore, the present invention provides a layered tablet which prevents collapse of a layer including an acid scavenger from being delayed after preservation, and prevents tableting problems such as binding, capping, and the like from occurring. The layered tablet of the present invention comprises: a layer (α) including (A) a propionic acid-based, non-steroidal-based anti-inflammatory agent or salt thereof, and substantially not including (B) an acid scavenger; and a layer (β) substantially not including (A) the propionic acid-based, non-steroidal-based anti-inflammatory agent or salt thereof, and including one or more selected from (B) the acid scavenger, and (C) sugar and sugar-alcohol, and (D) a disintegrant.</p> |
