发明名称 MURINE MODELS FOR EVALUATION OF RUTHENIUM COMPOUNDS-BASED THERAPEUTIC STRATEGIES IN CANCER
摘要 <p>The invention relates to a method for evaluation of anti-tumour effects of ruthenium (III) compounds. According to the invention, the method comprises the inoculation of 1 x 10tumour cells/ml in the right flank of a laboratory animal and, 4 days after the implant, the initiation of an anti-tumour treatment based on a Ru compound, by administering 75 mg/kg of body weight, 3 times a week, for 3 weeks while monitoring weekly the weight, the tumour size and the biochemical parameters of oxidative stress in serum and tissues.</p>
申请公布号 RO130588(A2) 申请公布日期 2015.09.30
申请号 RO20130000990 申请日期 2013.12.16
申请人 INSTITUTUL ONCOLOGIE PROF.DR.ALEXANDRU TRESTIOREANU 发明人 GRUIA MARIA IULIANA;UIVAROSI VALENTINA;NEGOIŢĂ VALENTINA;VASILESCU MONICA;DUMITRU MIRELA;GLAVAN DANIELA;NIŢU CRISTINA;PANAIT MARIETA
分类号 G01N33/50 主分类号 G01N33/50
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