| 发明名称 |
IGM THERAPY IN PREVENTION OF ONSET, PROGRESSION, AND RECURRENCE OF AUTOIMMUNE TYPE 1 DIABETES |
| 摘要 |
The therapeutic potential of polyclonal serum naturally occurring IgM (nIgM) administration in preventing the onset and progression of autoimmune type 1 diabetes and in promoting graft survival following islet allotransplantation has been investigated. nIgM therapy prevents both, onset and progression of diabetes and promotes islet graft survival. |
| 申请公布号 |
US2015265704(A1) |
申请公布日期 |
2015.09.24 |
| 申请号 |
US201314434179 |
申请日期 |
2013.10.08 |
| 申请人 |
UNIVERSITY OF VIRGINIA PATENT FOUNDATION |
发明人 |
Brayman Kenneth;Chhabra Preeti;Lobo Peter I. |
| 分类号 |
A61K39/395;A61K35/39;A61K45/06;C07K16/06 |
主分类号 |
A61K39/395 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A method of preventing or treating Type 1 Diabetes, said method comprising administering to a subject in need thereof a pharmaceutical composition comprising an effective amount of naturally occurring IgM (nIgM), a pharmaceutically-acceptable carrier, and optionally at least one additional therapeutic agent. |
| 地址 |
Charlottesville VA US |
