主权项 |
1. A compound having the formula: or a pharmaceutically acceptable salt thereof, wherein each dotted line represents an optional and additional bond, such that only one optional and additional bond can be attached to each of Y1 and Y2, and wherein: A is imidazole or benzimidazole, wherein said imidazole group or said benzimidazole group can be optionally and independently substituted on one or more ring nitrogen atoms with R1 and on one or more ring carbon atoms with R3; D is imidazole or benzimidazole, wherein said imidazole group or said benzimidazole group can be optionally and independently substituted on one or more ring nitrogen atoms with R2 and on one or more ring carbon atoms with R4; L1 and L2 are each independently selected from a bond, C1-C4 alkylene, —NH—, —C(O)—, —NHC(O)— and —S(O)2—; the group:is selected from: each occurrence of R1 is independently —C1-C6 alkyl, —C1-C6 haloalkyl, -(3 to 7-membered cycloalkyl) or -(4 to 7-membered heterocycloalkyl); each occurrence of R2 is independently —C1-C6 alkyl, —C1-C6 haloalkyl, -(3 to 7-membered cycloalkyl) or -(4 to 7-membered heterocycloalkyl); R3 and R4 are each independently selected from: each occurrence of R5 is independently: each occurrence of Ra is independently H, C1-C6 alkyl, haloalkyl, cycloalkyl or aryl; and each occurrence of Rb is independently C1-C6 alkyl, such that the compound of formula (I) contains at least one R3 group and at least one R4 group. |