| 发明名称 |
TRANSCRIPTIONAL GENE SILENCING OF ENDOGENES IN PLANTS |
| 摘要 |
The present invention relates to transcriptional gene silencing (TGS) of endogenes in plants, plant tissue and plant cells. More specifically, the present invention relates to nucleic acid constructs that are capable of TGS of endogenes in plants, plant tissue and plant cells. The present invention further relates to methods of reducing endogenous gene expression in plants, plant tissues or plant cells by TGS using the nucleic acid constructs of the invention. |
| 申请公布号 |
US2015252375(A1) |
申请公布日期 |
2015.09.10 |
| 申请号 |
US201314426096 |
申请日期 |
2013.08.27 |
| 申请人 |
THE ROCKEFELLER UNIVERSITY |
发明人 |
Chua Nam-Hai;Deng Shulin;Dai Hongzheng;Niu Qi-Wen;Wang Huan;Arenas Huertero Catalina |
| 分类号 |
C12N15/82 |
主分类号 |
C12N15/82 |
| 代理机构 |
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代理人 |
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| 主权项 |
1. A nucleic acid construct comprising a plant operable promoter operatively linked to a nucleic acid silencer molecule operatively linked to plant operable 3′ regulatory region, wherein the nucleic acid silencer molecule comprises at least one promoter region of a plant endogene target, wherein expression of the nucleic acid silencer molecule in a transgenic plant results in transcriptional gene silencing of the plant endogene target. |
| 地址 |
New York NY US |
