发明名称 ヘテロプラスミー細胞をホモプラスミー化する方法
摘要 <p>A method includes providing a eukaryotic cell including mutant mtDNA in which there is at least one mutation in the mtDNA, allowing the cell to come into contact with an active oxygen species or a chemical species that generates such an active oxygen species in the cell (e.g., hydrogen peroxide) and thereby changing the percentage of mutant mtDNA (mitochondrial genomic DNA) in the cell as a result of the contact. Also featured are cells obtained by the above-described method.</p>
申请公布号 JP5777081(B2) 申请公布日期 2015.09.09
申请号 JP20090285729 申请日期 2009.12.16
申请人 国立研究開発法人理化学研究所;国立研究開発法人国立精神・神経医療研究センター 发明人 凌 楓;柴田 武彦;牛 栄;吉田 稔;後藤 雄一
分类号 C12N5/10 主分类号 C12N5/10
代理机构 代理人
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