Methods for treating HCV

摘要

The present invention features interferon-free therapies for the treatment of HCV. Preferably, the treatment is over a shorter duration, such as no more than 12 weeks. In one aspect, the therapies comprise administering at least two direct acting antiviral agents and ribavirin to a subject with HCV infection. For example, the therapies comprise administering to the subject effective amounts of therapeutic agent 1, therapeutic agent 2 (or therapeutic agent 3), an inhibitor of cytochrome P450 (e.g., ritonavir), and ribavirin. 6722761_1 (GHMatters) P99395.AU.6 JBORHAM 150 mu~ QD Coinpowid I + 400 iuzBDCrp--ai- -i- 5 u V/Q Compotad 4 S250 ig QD Compound 1 +400 ng BI Coip ond 2 g 25 tug QD Compound 4 > co 6 8 10 12 16 24 Time (weeks) Figure 6C