发明名称 METHOD FOR PREDICTION OF STABLE VIROLOGICAL RESPONSE TO ANTI-VIRAL THERAPY OF CHRONIC VIRAL HEPATITIS C ACCOMPANYING HIV INFECTION
摘要 FIELD: medicine.SUBSTANCE: co-infected patients are examined to assess the dynamics of immunological markers of interferon ? (IFN?), interferon ? (IFN?) and interleukin 4 (IL-4) and their monitoring before therapy and 4 weeks after the beginning of the therapy. A stable remission is predicted if the initial cytokine count is more than 3.99 pg/ml for IFN?, from 8.32 to 13.1 pg/ml for IFN?, if the IFN?/IL-4 ratio is more than 6.72, whereas IFN? tends to increase as many as 100 times 4 weeks after the beginning of the therapy with IFN? of 8.32 to 13.1 pg/ml, and the IFN?/IL-4 ratio keeps increasing in the course of treatment by more than 6.72.EFFECT: using the given method enables the early prediction of the clinical outcome of antiviral therapy in HIV patients.2 ex, 4 tbl, 3 dwg
申请公布号 RU2558793(C2) 申请公布日期 2015.08.10
申请号 RU20130152050 申请日期 2013.11.21
申请人 GOSUDARSTVENNOE BJUDZHETNOE OBRAZOVATEL'NOE UCHREZHDENIE VYSSHEGO PROFESSIONAL'NOGO OBRAZOVANIJA "TIKHOOKEANSKIJ GOSUDARSTVENNYJ MEDITSINSKIJ UNIVERSITET" MINISTERSTVA ZDRAVOOKHRANENIJA ROSSIJSKOJ FEDERATSII (GOU VPO TGMU MINZDRAVA ROSSII) 发明人 LI JULIJA ALEKSANDROVNA;SKLJAR LIDIJA FEDOROVNA;MARKELOVA ELENA VLADIMIROVNA
分类号 G01N33/53 主分类号 G01N33/53
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