发明名称 |
STABILIZATION OF BIOMOLECULES BY ATTACHMENT OF RESPONSIVE POLYMERS AND SENSORS THEREOF |
摘要 |
The present invention provides a biomolecule conjugate having one or more functionalized biomolecules wherein the biomolecule is functionalized with one or more reactive sites, and at least one polymer capable of undergoing a polymer growth reaction, wherein the polymer is attached to at least one of the reactive sites of the functionalized biomolecule and wherein the polymer envelopes the functionalized biomolecule to form a reversible nanoparticle structure which protects the biomolecule by dynamically collapsing to preserve the biomolecule when an adverse environmental stimulus is present. A method of protecting a biomolecule from environmental conditions is also provided. |
申请公布号 |
WO2015112302(A1) |
申请公布日期 |
2015.07.30 |
申请号 |
WO2014US72183 |
申请日期 |
2014.12.23 |
申请人 |
FLIR DETECTION, INC. |
发明人 |
WALKER, JEREMY P.;WILSON, DAVID C.;LEECH, ANNA M.;SINCLAIR, JESSICA J. |
分类号 |
A61K31/74 |
主分类号 |
A61K31/74 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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