Fourier tickling for homonuclear decoupling in NMR

摘要

A method for high resolution NMR (=nuclear magnetic resonance) measurements using the application of excitation pulses and the acquisition of data points, whereby a dwell time Δt separates the acquisition of two consecutive data points, which is characterized in that one or more tickling rf (=radio frequency) pulses of duration τp are applied within each dwell time Δt, and that the average rf field amplitude of each of the tickling rf pulses approximately fulfills the condition ω1=ω1τp/Δt=πJ wherein J is the scalar J-coupling constant and ω1=γB1 with γ being the gyromagnetic ratio and B1 being the strength of the magnetic component of each tickling rf pulse. This method is effective in decoupling homonuclear couplings.

主权项

1. A method for high resolution NMR (=nuclear magnetic resonance) measurements, the method comprising the steps of:
a) applying an excitation pulse; b) acquiring a first data point; c) waiting a dwell time Δt; d) applying, during step c), one or more tickling rf (=radio frequency) pulses of duration τp, each tickling rf pulse having an average rf field amplitude between ω1=ω1τp/Δt=π/10J and ω1=ω1τp/Δt=10πJ, wherein J is a scalar J-coupling constant and ω1=γB1 with γ being a gyromagnetic ratio and B1 being a strength of a magnetic component of each tickling rf pulse; and e) acquiring a second data point immediately following completion of step c), the dwell time Δt thereby separating acquisition of the first and the second data points.