METHOD FOR ANALYSIS OF COMPOUNDS WITH AMINO GROUP AND ANALYTICAL REAGENT THEREFOR

摘要

There is provided a method for the analysis of a compound with amino group such as amino acid and peptide contained in a sample and convenient manner with a high sensitivity. The compound with amino group in a sample containing the compound with amino group is labeled with a specific carbamate compound such as p-trimethylammonium anilyl-N-hydroxysuccinimidyl carbamate iodide to enhance the selectivity whereby it is analyzed easily and conveniently with a high sensitivity. Particularly by means of mass spectrometry such as MS/MS method, the aimed compound is able to be quantitatively analyzed. There are further provided a labeling reagent for mass spectrometry used therefor and a novel compound which is able to be used for the labeling reagent.