| 发明名称 | Peptide compositions and therapeutic uses thereof | ||
| 摘要 | Compounds comprising R-G-Cysteic Acid (i.e., R-G-NH—CH(CH2—SO3H)COOH or Arg-Gly-NH—CH(CH2—SO3H)COOH) and derivatives thereof, including pharmaceutically acceptable salts, hydrates, stereoisomers, multimers, cyclic forms, linear forms, drug-conjugates, pro-drugs and their derivatives. Also disclosed are methods for making and using such compounds including methods for inhibiting cellular adhesion to RGD binding sites or delivering other diagnostic or therapeutic agents to RGD binding sites in human or animal subjects. | ||
| 申请公布号 | US9018352(B2) | 申请公布日期 | 2015.04.28 |
| 申请号 | US201012943900 | 申请日期 | 2010.11.10 |
| 申请人 | Allegro Pharmaceuticals, Inc. | 发明人 | Mackel Michael J.;Park John |
| 分类号 | C07K7/00;A61K9/08;A61K38/17;A61K47/48;A61K51/06;A61K51/08;A61L27/22;A61L31/04;A61K9/06 | 主分类号 | C07K7/00 |
| 代理机构 | Stout, Uxa & Buyan, LLP | 代理人 | Buyan Robert D.;Stout, Uxa & Buyan, LLP |
| 主权项 | 1. A compound comprising a peptide, wherein the peptide comprises Glycine-Arginine-Glycine-Cysteic(Acid)-Threonine-Proline. | ||
| 地址 | San Juan Capistrano CA US | ||